Meloxicam Injection 2%

COMPOSITION: Each ml contains
Meloxicam   20mg
Solvents ad   1 ml.

PHARMACOLOGY: Meloxicam is a Non-Steroidal Anti-Inflammatory Dug(NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, anti-exudative, analgesic and antipyretic effects. It reduces leukocyte infiltration into the inflamed tissue. To a minor extent it also inhibits collagen-induced thrombocyte aggregation.
Meloxicam also has anti-endotoxic properties because it has been shown to inhibit production of thromboxane B2 induced by E.coli endotoxin administration in calves, lactating cows and pigs.

INDICATIONS
Cattle:For use in acute respiratory infection with appropriate antibiotic therapy to reduce clinical signs in cattle.
For use in diarrhea in combination with oral re-hydration therapy to reduce clinical signs in calves of over one week of age and young, non-lactating cattle.
For adjunctive therapy in the treatment of acute mastitis, in combination with antibiotic therapy.
For the relief of post-operative pain following dehorning in calves.

Pigs:For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation.
For adjunctive therapy in the treatment of puerperal septicaemia
and toxaemia(mastitis-metritis-agalactia syndrome) with appropriate antibiotic therapy.

Horses:For use in the alleviation of inflammation and relief of pain in both acute and
chronic musculo-skeletal disorders.
For the relief of pain associated with equine colic.

ADMINISTRATION AND DOSAGE
Cattle:Single subcutaneous or intravenous injection at a dosage of 0.5mg meloxicam/kg body weight(i.e.2.5ml/100kg body weight) in combination with antibiotic therapy or with oral re-hydration therapy,as appropriate.
Pigs:Single intramuscular injection at a dosage of 0.4mg meloxicam/kg body weight(i.e. 2.0ml/100 kg body weight) in combination with antibiotic therapy, as appropriate.If required, a second administration of meloxicam can be given after 24hours.
Horses:Single intravenous injection at a dosage of 0.6mg meloxicam/kg body weight(i.e.3.0ml/100kg body weight).
For use in the alleviation of inflammation and the relief of pain in both acute and chronic
musculo-skeletal disorders,a suitable oral therapy containing meloxicam,administered in accordance with label recommendations,may be used for continuation of treatment.
Do not breach the vial more than 50 times.

WITHDRAWAL TIME
Cattle: Meat and offal: 15days; Milk: 5days
Pigs: Meat and offal: 5 days
Horses: Meat and offal: 5days.
Not authorized to use in horses producing milk for human consumption.
Shelf life: 3 years

STORAGE: Protect from light and store in a cool dry place and below 30ºC.